Human Behavioral Pharmacology Laboratory

University of Chicago

Department of Psychiatry and Behavioral Neuroscience


Jessica Weafer, Ph.D.


July 2012 - present: Postdoctoral Scholar, HBPL, Department of Psychiatry, University of Chicago
2012: Ph.D., Experimental Psychology, University of Kentucky
2008: M.A., Experimental Psychology, University of Kentucky
2004: B.A., Psychology, Boston University

Research Interests:

My research focuses broadly on the role of behavioral impulsivity in drug abuse. That is, I am interested in how impulsivity may be both a risk factor for drug use as well as a result of drug use. I am currently investigating the relationship between trait-level impulsive behavior and sensitivity to drug reward, as heightened sensitivity could contribute to increased risk for drug abuse in impulsive individuals. I am also interested in the acute effects of drugs and drug cues on inhibitory control, and how sensitivity to state-level changes in impulsivity relates to risk for drug abuse. Ultimately, I hope to combine behavioral, neuroimaging, and genetic techniques to better understand the mechanisms that put impulsive individuals at increased risk for drug abuse.


Weafer J., Mitchell SH, and de Wit H (2014) Recent Translational Findings on Impulsivity in Relation to Drug Abuse. Current Addiction Reports

Weafer J, and de Wit H (in press) Sex differences in impulsive action and impulsive choice. Addictive Behaviors

Weafer J, Burkhardt A, and de Wit H (in press) Sweet taste liking is associated with impulsive behavior in humans. Frontiers in Behavioral Neuroscience

Weafer J, and MT Fillmore (in press) Alcohol-related cues potentiate alcohol impairment of behavioral control in drinkers. Psychology of Addictive Behaviors

Roberts W, Miller MA, Weafer J, and Fillmore MT (2014) Heavy drinking and the role of inhibitory control of attention. Experimental and Clinical Psychopharmacology 22:133-140.

Weafer J, Gallo D, and de Wit H (2014) Amphetamine fails to alter cued recollection of emotional images: Study of encoding, retrieval, and state-dependency. PLoS One 9:e90423.

Weafer J, Baggott MJ, and de Wit H (2013) Test-retest reliability of behavioral measures of impulsive choice,impulsive action, and inattention. Experimental and Clinical Psychopharmacology 21:475-481.

Weafer J, and de Wit H (2013) Inattention, impulsive action, and subjective response to d-amphetamine. Drug and Alcohol Dependence 133:127-133.

Weafer J, Fillmore MT (2013) Acute alcohol effects on attentional bias in heavy and moderate drinkers. Psychology of Addictive Behaviors PMID: 22732051.

Weafer J, Fillmore MT (2012) Comparison of alcohol impairment of behavioral and attentional inhibition. Drug and Alcohol Dependence Jun 4 [Epub ahead of print]PMID: 22673197.

Weafer J, Fillmore MT (2012) Alcohol-related stimuli reduce inhibitory control of behavior in drinkers. Psychopharmacology 222:489-98. PMID: 22358851

Weafer J, Fillmore MT (2012) Acute tolerance to alcohol impairment of behavioral and cognitive mechanisms related to driving: drinking and driving on the descending limb. Psychopharmacology 220:697-706. PMID: 21960182

Fillmore MT, Weafer J (2011) Acute tolerance to alcohol in at-risk binge drinkers. Psychology of Addictive Behaviors Oct 24 [Epub ahead of print] PMID: 22023021

Weafer J, Milich R, Fillmore MT (2011) Behavioral components of impulsivity predict alcohol consumption in adults with ADHD and healthy controls. Drug and Alcohol Dependence 113:139-146. PMID: 20863628

Weafer J, Miller MA, Fillmore MT (2010) Response conflict as an environmental determinant of gender differences in sensitivity to alcohol impairment. Current Drug Abuse Reviews 3:147-155. PMID: 20500155

Miller MA, Weafer J, Fillmore MT (2009) Gender differences in alcohol impairment of simulated driving performance and driving related skills. Alcohol and Alcoholism 44:586-593. PMID: 19786725

Weafer J, Fillmore MT, Milich R (2009) Increased sensitivity to the disinhibiting effects of alcohol in adults with ADHD. Experimental and Clinical Psychopharmacology 17:113-121. PMID: 19331488

Weafer J, Fillmore MT (2008) Alcohol impairment of inhibitory mechanisms: Individual differences in acute impairment of inhibitory control predict ad libitum alcohol consumption. Psychopharmacology 201:315-324. PMID: 18758758

Weafer J, Camarillo D, Fillmore MT, Milich R, Marczinski CA (2008) Simulated driving performance of adults with ADHD: Comparisons with alcohol intoxication. Experimental and Clinical Psychopharmacology 16:251-263. PMID: 18540785

Palfai TP, Weafer J (2006) College student drinking and meaning in the pursuit of life goals. Psychology of Addictive Behaviors 20:131-134. PMID: 16784355

Fillmore MT, Weafer J (2004) Alcohol impairment of behavior in men and women. Target Article. Addiction 99:1237-1246. PMID: 15369556